GV1001, an hTERT-Derived Peptide, Prevents Cisplatin-Induced Nephrotoxicity by Preserving Mitochondrial Function. (PubMed, Cells) - Nov 26, 2025 - "Collectively, these findings demonstrated that GV1001 might protect kidney from cisplatin through maintaining mitochondrial structure and function and suppressing downstream injury cascades in renal epithelial cells. By directly targeting the mitochondrial mechanisms underlying cisplatin toxicity, GV1001 represents as a promising therapeutic strategy to mitigate CIN and improve the safety of cisplatin-based chemotherapy."
Journal • CNS Disorders • Renal Disease
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Cheyenne Beheshtian; No-Hee Park; Reuben Kim; Sangjae Kim; Seojin Kim; Wei Chen
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